Biomolecular Structure

Professor

  • MORIMOTO Yukio , e-mail: morimoto.yukio.3z

Associate Professor

  • CHATAKE Toshiyuki, e-mail: chatake<atmark>

Assistant Professors

  • KITA Akiko, e-mail: kita<atmark>
  • KAWAGUCHI Akio, e-mail: akawaguchi<atmark>

replace* with @kyoto-u.ac.jp ,<atmark> with @rri.kyoto-u.ac.jp

The crystal structure analysis by quantum beams, X-ray, synchrotron, electron and neutron, is the most powerful technique to investigate and clarify the structure and function of bio- or supra-macromolecule at the atomic resolution, and its effect is more accelerated by collaboration with other methods, such as electron diffraction or cryo-electron microscopic methods. We have concentrated on X-ray, synchrotron radiation, electron and neutron studies of structural biology of the macromolecule from viewpoints of hydrogen atoms and bonds, strategic structural research especially to bio-medicals and engineering materials for protein complexes under the crystal and/or solutions, the structure of various kinds of polymeric or drugs. Also we have actively collaborated with other high-flux neutron facilities: J-PARK(Tokai), SNS-HFIR(OakRidge), ANSTO(Australia), and SLS(Swiss), SPring-8(Harima), PF(Tsukuba) for synchrotron radiation sources.

Deuterium in the human blood hemoglobin molecule by cross-section density maps calculated from neutron diffraction data.

Fig. 1. Deuterium in the human blood hemoglobin molecule by cross-section density maps calculated from neutron diffraction data.